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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKG1
All Species:
19.39
Human Site:
Y497
Identified Species:
60.95
UniProt:
Q13976
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13976
NP_001091982.1
671
76364
Y497
L
I
L
D
H
R
G
Y
A
K
L
V
D
F
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851997
510
57367
H374
E
I
I
L
N
K
G
H
D
I
S
A
D
Y
W
Cat
Felis silvestris
Mouse
Mus musculus
P0C605
671
76332
Y497
L
I
L
D
H
R
G
Y
A
K
L
V
D
F
G
Rat
Rattus norvegicus
Q64595
762
87163
Y589
L
I
L
D
A
D
G
Y
L
K
L
V
D
F
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q03043
1088
121322
Y914
L
L
L
N
E
R
G
Y
V
K
L
V
D
F
G
Honey Bee
Apis mellifera
NP_001011581
678
77281
Y504
L
L
L
D
S
Q
G
Y
V
K
L
V
D
F
G
Nematode Worm
Caenorhab. elegans
O76360
780
86723
Y606
C
L
L
A
N
T
G
Y
L
K
L
V
D
F
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P06245
380
44201
K244
I
T
T
K
P
Y
N
K
S
V
D
W
W
S
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
68.6
N.A.
99.5
48.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
40.9
61.2
45.1
N.A.
Protein Similarity:
100
N.A.
N.A.
72.2
N.A.
99.8
65.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
51.1
75.9
61.6
N.A.
P-Site Identity:
100
N.A.
N.A.
20
N.A.
100
80
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
73.3
73.3
60
N.A.
P-Site Similarity:
100
N.A.
N.A.
53.3
N.A.
100
80
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
86.6
86.6
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
13
13
0
0
0
25
0
0
13
0
0
0
% A
% Cys:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
50
0
13
0
0
13
0
13
0
88
0
0
% D
% Glu:
13
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
75
0
% F
% Gly:
0
0
0
0
0
0
88
0
0
0
0
0
0
0
75
% G
% His:
0
0
0
0
25
0
0
13
0
0
0
0
0
0
0
% H
% Ile:
13
50
13
0
0
0
0
0
0
13
0
0
0
0
0
% I
% Lys:
0
0
0
13
0
13
0
13
0
75
0
0
0
0
0
% K
% Leu:
63
38
75
13
0
0
0
0
25
0
75
0
0
0
13
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
13
25
0
13
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
38
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
13
0
0
0
13
0
13
0
0
13
0
% S
% Thr:
0
13
13
0
0
13
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
25
13
0
75
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
13
13
0
13
% W
% Tyr:
0
0
0
0
0
13
0
75
0
0
0
0
0
13
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _